ADCs @ ASCO: concerns over Dato-DXd in 1L Lung; GILD 2L OS as bad as AZN; SKB high ORR in unusual trial
MRNA/MRK: ASCO cancer vaccine data does not address pre-treatment imbalances that may be driving result
Oct 17, 2016PD1 Combos at ESMO good for AZN and BMY not for MRK and ROGChemo combos continue to look equivocal, while IO combos remain durable as MYSTIC’s shadow clears New ESMO lung cancer data bodes well...
Oct 13, 2016Unravelling the MYSTICalAstra's underappreciated oncology pipeline stalking the market We initiate on AstraZeneca with an overweight rating and a Target Price of...
Aug 8, 2016Consensus PD1 hopes under threatPD1 market continues to shrink, but Bristol’s failure not good news for rivals BMY announced Friday that its pivotal phase III study of...
May 26, 2016ASCO data closing in on PD1 marketNew ASCO 2016 data continues to support lower than consensus potential revenues, modest anti PD-L1 efficacy and more doubts over chemo...
Apr 6, 2016Short sharp targeted treatment may take the sting out of PD-1 marketAnti PD-1 commercial potential still appears vastly overestimated With PD-1 checkpoint inhibition clearly set to improve the landscape of...
Nov 23, 2015MRK.US: First anti-IDO/PD1 data appears no better than current standard of careMuch anticipated IDO+PD1 combo data faces high hurlde... IDO inhibition is one of many newer immunotherapies that are beginning to enter...
Oct 1, 2015BMY.US: Opdivo +Yervoy restricted to BRAF wild types by FDA despite good activity in mutants…Implications for 2nd line non-squamous lung? It is interesting to note that this morning’s approval of Opdivo + Yervoy in 1st line...
ADCs @ ASCO: concerns over Dato-DXd in 1L Lung; GILD 2L OS as bad as AZN; SKB high ORR in unusual trialJul 1
MRNA/MRK: ASCO cancer vaccine data does not address pre-treatment imbalances that may be driving resultJun 18