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ROG.VX: Perjeta's precarious premise, ambitious Esbriet aspirations
![Foveal](https://static.wixstatic.com/media/f1a3c6_37373f809ffc45df98142e3fc76d50b4.jpg/v1/fill/w_980,h_551,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/f1a3c6_37373f809ffc45df98142e3fc76d50b4.jpg)
Initiation of Coverage of Roche: Underweight - Target Price CHF235
We see major risks over Herceptin add-on Perjeta in breast cancer (critical to sustaining leadership and growth in HER2 cancer with impending biosimilars), along with limited prospects for newly acquired Esbriet that leaves us 10-14% below cons EPS in 2017-18.