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ROG.VX: Ocrelizumab breakthrough in PPMS may not be effective in all
Ocrelizumab likely very effective in half the overall PPMS population, as is Rituxan
Given both Rituxan and ocrelizumab have a near identical mechanism of action, we examine the reasons why Rituxan failed in 2009 but ocrelizumab did not in 2015 and find that ocrelizumab may not be effective in all PPMS
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